FacebookTwitterCopy LinkEmail RONALD RIECKENASHELY HAMMERDAVID DK WELLSTODD MORHANRICK TOMLINSONSHON ROESUSIE NHEERDINKDARREN STRATMANPAUL M BACKSTAGEGINI EATANBROCK LANCETOMMY BARNETTJAMES KELLYDARLA M MILLIGANJAIME A GRAHAMBRADLEY SMITHJACK DAVISCHRISTINA WICKSUSIE HEERDINKDARREN STRATMANED GOEBELJOHN MILLERKALAH GEORGETTE-VOWELJOE TEMPLETONSTEVEN PIRNATEDIASRISINTA ARIYANTIEVELYN K GRAVESMARY DAVISBRENT FEULNERJOHN LUEDKEC LARRY RHODESJAMIE FUCHSED KARGESAMANDA HENNKEN HAYNIEBRANDEE L. MURPHYAMANDA HERNNKELLY CHANLERPHILLIP DAVISCAROL CHRISTINE BARTLEYKELLYN GATESDONNA ROBINSONCHARLES D EUBANKSJESS DANIELSJORDAAN BAERCORY RAYLON WALTERSRANDALL FOSTERTINA PORTELLOSUNNI ZIMMERKRISTEN KATHLEEN TUCKERKELLY GATESDONNA ROBINSONCHARLES D. EUBANKSJESSE DANIELCORY RAY
overseas governments or quasi government bodies overseas charities, non-governmental organisations or non-profit organisations (NGOs/NPOs) other overseas institutions (for example private company donations) individual donors resident overseas unknown Certain questions will be optional in 2018, but compulsory in 2019.If you are submitting your annual return for the first time, or you are not sure what you need to include, read guidance about how to prepare and submit your annual return.Why we are asking about salaries and benefits in charitiesOur research into public trust and confidence in charities shows that the public is concerned about high levels of pay in charities.Because of this we will be asking charities to provide more information about salaries to increase accountability.We will ask for a breakdown of salaries across income bands, and the amount of total employee benefits for the highest paid member of staff.But, in response to concerns raised during our public consultation, we will not publish details of benefits given to the paid member of staff on the charity register.Why we are asking about overseas expenditureWe will build on the current annual return questions about charitable expenditure overseas, to establish how charities transfer and monitor funds sent overseas.We are doing this because all money transfer processes bear risks, and it’s important that charities take appropriate steps to manage these.We recognise that some charities will need to make changes to their record keeping to answer parts of this question. For this reason the questions about methods of transferring money outside the regulated banking system, and about monitoring controls and risk management, will be optional for the 2018 annual return.These questions will be mandatory for the annual return 2019 onwards.Why we are asking about income from outside the UKTo get a better understanding of the income sources from outside of the UK, we are introducing questions about the breakdown of sources of income from each country a charity receives funds from.The options we’ve provided for you to choose from are: Some charities will need to make changes to their financial systems to collect and sort the information more easily.For this reason, we have made those parts of the question set relating to other private institutions outside the UK (other than charities, Non-Governmental Organisations and Non-Profit Organisations) and individual donors outside the UK optional to answer for the 2018 annual return.These questions will be mandatory from 2019 onwards. all 2018 and 2019 annual return questions (ODT, 37.8KB) If you submitted your latest annual return before 12 November 2018, the next time you log in to this service you will be asked to check and update all your charity details. Find out what you need to do. The 2018 and 2019 annual return includes new questions which you can view before you log in.
Load remaining images Electric Beethoven brought some serious jams to New York, NY last night (10/26), playing an extended performance for enthusiastic fans at the DROM venue. The four piece group – Reed Mathis, Todd Stoops, Jay Lane and Clay Welch – were originally scheduled for two nights in NYC, but one of their shows was unfortunately cancelled at the last minute when the Cutting Room booked a Dave Chappelle residency.No matter, because the Electric Beethoven crew instead extended their performance at DROM last night, spending over fours jamming on stage. They had planned to play Beethoven’s Symphony No. 3 and No. 6 at the show, but instead only got through No. 3. That only proves that this band loves to jam!Watch an extended video of Electric Beethoven’s performance at DROM below, courtesy of LazyLightning55a.A full gallery of iamges from the show can be seen below as well, courtesy of Chris Capaci.
Jam rockers The Jauntee continue their live series today, with the release of their Live Jaunt album from the Paradise Rock Club in Boston, MA. The show on 11/25/16 was support from Twiddle, and featured some great work from the up and coming jammers.Check out the show on Bandcamp, with a pay-what-you-want download, or stream the tracks below.<a href=”http://thejauntee.bandcamp.com/album/2016-11-25-paradise-rock-club-boston-ma”>2016-11-25 – Paradise Rock Club – Boston, MA by The Jauntee</a>Setlist: The Jauntee | Paradise Rock Club | Boston, MA | 11/25/16Dirty George >Dirty Job*Mammoth RelaxesBlack Bart ->Hey Pocky A-Way+ ->When the Love Is#I Wanna Love You* “Butterfly” tease+ “Puppy In My Pocket” tease and jam, “Little Drummer Boy” tease# “Streets of Cairo” teaseDon’t miss The Jauntee with Digital Frontier on Valentine’s Day at American Beauty! Tickets are available here.
Back in February, Phish announced that their 11th festival, Curveball, would be headed to Watkins Glen International in New York from August 17th to 19th. At many of Phish’s past multi-day festivals, the band has hosted 5K races, and Curveball will be no different. Today, Curveball has announced “The 102nd Running of the First Annual Runaway Jim Memorial 5k Road Race,” which will fall on Saturday, August 18th, of the festival.Pre-registration for the Runaway Jim Memorial 5k Road Race is open now and available on a first-come, first-registered basis here. As noted in the announcement,Officially Registered runners receive a numbered race bib for official timing. Race entry is free to all ticket holders (with the option of buying a racing shirt during online registrations). We encourage runners to pre-register online as only limited registration may be available at Watkins Glen. Trophies will be awarded to the fastest Male and Female, and the 2nd and 3rd place finishers overall. Medals will be awarded to the top finisher in each age category: 18-29, 30- 39, 40-49, 50-59, 60 and above.Perhaps most importantly, as noted in the festival’s announcement, “Drug testing will not take place before and after the race.” For more information and to register for Curveball’s The 102nd Running of the First Annual Runaway Jim Memorial 5k Road Race, head here. For more information on Curveball, which is scheduled for August 17th to 19th in Watkins Glen, NY, head to the festival’s website here.
After decades on the front lines of the HIV pandemic, Max Essex has seen his share of both setbacks and victories.There have been far too many deaths, some among colleagues in Botswana, where the Harvard AIDS researcher does much of his work. There have been frustrating years in the lab searching for a vaccine to master the disease, with nothing so far to show for it in clinics and hospital wards.But there have also been important successes, such as the research that showed anti-retroviral drugs given to pregnant or breastfeeding women can stop HIV transmission to their babies. Today, that practice can protect more than 98 percent of such babies — better than the best vaccines.The use of drug treatment to prevent new infections was further validated in research on so-called discordant couples, where just one partner is infected with HIV. Studies, including those conducted in part by Essex and the Harvard School of Public Health AIDS Initiative (HAI), have shown that treating the infected partner with powerful antiretroviral drugs can prevent transmission to the non-infected partner.Those victories, and similar work by researchers around the world, have fueled the latest attempt to corral HIV. The strategy, called “treatment as prevention,” seeks to apply smaller successes to the whole population, using early, enhanced drug treatment both to treat the sick and to keep the virus at levels low enough to reduce transmission, with the hope of choking off the pandemic.Treatment as prevention has been gaining sway in the global AIDS community in recent years. In 2011, then-Secretary of State Hillary Clinton hailed it as a possible route to “an AIDS-free generation,” and it was included in the State Department’s 2012 blueprint toward that goal. But whether it can actually work to reduce infection at the community level remains an open question.Essex, who is the head of HAI and the Mary Woodard Lasker Professor of Health Sciences, has joined with a group of collaborators on a massive trial to test the strategy scientifically. The trial is needed to confirm that a strategy proven successful in smaller, targeted groups will work in the general population. It is also needed to provide the kind of solid scientific footing required to persuade governments to fund a major expansion of drug treatment worldwide.The Botswana Combination Prevention Project —“Ya Tsie” in Setswana, the country’s dominant language — is an enormous undertaking. It involves partners from HSPH, the Botswana Ministry of Health, the Botswana-Harvard Partnership, and the U.S. Centers for Disease Control and Prevention, and is funded through the U.S. government’s PEPFAR program. After two years of preparation, it is in the process of enrolling more than 100,000 people, age 16 to 64, living in 30 villages across the country.“It’s a big trial, obviously,” Essex said, “and it’s part of an approach most people recognize as important in the future, using treatment interventions as prevention.”The trial villages are paired with control villages getting the current standard of care, though with the latest in medical record-keeping and improvements in medical equipment and supplies. The villages where treatment as prevention is being tested will receive a combination of several established strategies that researchers hope will prove more effective together than the sum of their parts. Among the strategies: in-home counseling and testing, mother-to-child interventions, and voluntary circumcision of uninfected men.The key intervention, however, will provide anti-retroviral drugs according to two measures, rather than just the one used as the current standard. The current standard is a measure of HIV’s destruction of immune cells, called “CD4 counts,” which have become medical shorthand for measuring progression of the disease. Counts below 350 CD4 cells per microliter of blood are a common threshold — and the one used in Botswana — at which anti-retroviral therapy starts.Essex thinks that if lowering infectivity is a key goal, then the standard should reflect infectivity, not how sick a person is. The best measure of that, he believes, is viral load, which tallies the number of copies of the virus in the bloodstream. That has direct bearing, he said, on how easy it is to infect a sex partner, and can be high even before CD4 counts fall enough to prompt government-funded antiretroviral drug therapy.“There’s pretty good evidence that viral load is the best correlate of transmission,” Essex said. “People without high viral load don’t transmit.”Those enrolled in the Ya Tsie trial will begin drug therapy when viral load tops 10,000 copies per milliliter of blood or when their CD4 counts drop below 350 cells per microliter.“There’s some overlap between CD4 and viral load, but there’s a significant number of people with high viral load but with CD4 even above 500,” Essex said. “We’re targeting people with high viral load but who are above the standard of care.”Victor De Gruttola, the chairman of HSPH’s Biostatistics Department and the Henry Pickering Walcott Professor of Biostatistics, said faculty and students have devoted years to refining statistical methods to aid in design, monitoring, and analysis of the trial. A key element is genetic tracking of the virus in study participants, which will provide insight about the extent to which viral strains circulate within and across villages, an important consideration in evaluating the success or failure of the intervention.“What we’d really like to know is what would happen if you rolled out the intervention to an entire sexual network,” De Gruttola said. “What we’re finding out is what actually does happen to HIV incidence in a village receiving the intervention that is surrounded by nonintervention villages. But studying viral genetic linkage provides a basis for estimating what the intervention’s effect would be if all nearby villages received the intervention.”De Gruttola said that is just one issue that statisticians and others involved in the study design have been considering. Another is the likelihood that participation in the trial won’t be equal — some groups, particularly young men, are more difficult to enroll than others.Data collection for the trial is expected to last four years, Essex said, followed by about a year of analysis before major findings can be released. Secondary analysis of the data will likely continue for years afterward, he said.Essex is hopeful that treatment as prevention can provide another tool to fight the AIDS pandemic, which even with significant progress in recent years still has an enormous impact, infecting some 24 percent of adults in Botswana. He is cautious, however, about the chances for a home run against the disease.Even if the intervention proves effective, it would still have to gain political backing to be included in government health programs, with cost a key factor — another reason Essex has decided to explore viral load as an indicator of when therapy should start, rather than just beginning therapy as soon after infection as possible, as other trials are investigating. Though the latter approach would doubtless have a dramatic effect on the disease’s spread, it would likely also be expensive enough to make rallying the necessary political support difficult. An expansion of treatment to just a subset of the population, one with a high likelihood of infecting others but not yet sick enough to qualify for drug treatment, may be more politically palatable.“We’ve had unbelievable progress with drugs since the early to mid-’90s, both from the standpoint of saving lives of people who’ve already progressed to disease and preventing mother-to-child transmission,” Essex said. “[But] convincing everyone that they can and should [support a new intervention] from the standpoint of resources, of policy … is never easy.”
Talk less. Listen more. The Hamilton cast album will be available digitally on September 25, but if that doesn’t satisfy you, go ahead and get your fix now. NPR has released a first listen of the entire recording. Take it all in as the young, scrappy and hungry Founding Father, some werk-ing Schuyler sisters, rapping cabinet members and more blow us all away. How lucky we are to be alive right now, indeed! The Atlantic Records album will be available in stores on October 16. Related Shows View Comments Hamilton from $149.00
Are you afraid to open your cupboard and look for those baking ingredients? Do you wonder if they are OK or should be thrown out? Do these items ever get old? If seasonal baking is all you do, those leftover baking ingredients may be less than fresh. Even if you bake throughout the year, staple ingredients should be refreshed periodically. Now is a good time of year to take inventory. Dry ingredients like sugar, most flours and spices are safe to use no matter how old they are. But they might not taste or perform as expected forever.FlourWhite flour keeps its quality up to a year when stored in an airtight container or freezer bag in a cool, dry place. Remember, moisture content can affect your recipe. All-purpose and bread flour will keep up to two years at 40 F in your refrigerator, according to the Wheat Foods Council. It can be stored indefinitely in the freezer. Allow refrigerated flour to come to room temperature before using it. Whole wheat flour keeps best for one to three months at room temperature. It becomes rancid if kept at room temperature for any longer. For longer storage, put it in an airtight container or freezer bag in the refrigerator or freezer. It will maintain quality six months in the refrigerator and up to 12 months in the freezer. SugarWhite granulated sugar keeps indefinitely if properly stored. However, rotate the supply every two years for ease of use and quality. Store it in an airtight container or a heavy moisture-proof plastic bag. To soften hardened sugar, put it in a sturdy food-quality bag and pound it with a hammer. Smash smaller pieces with a mortar and pestle or break in a spice grinder.Brown sugar keeps maximum freshness and flavor for four to six months. It’s important to store it in an airtight container to retain moisture and prevent hardening. Keep it in its original plastic bag, tightly closed, or transfer it to an airtight container or a moisture-proof plastic bag.To soften brown sugar, heat it in a 250-degree oven for a few minutes. Or, place it in a microwave-safe container and loosely covered with a white, damp paper towel. Microwave on high and check it every 30 seconds. Be very careful when handling heated sugar.Baking powder, sodaBaking powder and baking soda keep 12 to 18 months if stored tightly covered in a dry place. Discard both after expiration date. Use dry utensils to dip baking powder or soda. To test baking powder for freshness, mix one teaspoon baking powder with one-third cup of hot water. If it foams vigorously, it still has rising power. To test baking soda, place one and a half teaspoons in a small bowl with one tablespoon of vinegar. If it fizzes, it will still leaven food. If it doesn’t, place it in the refrigerator to trap odors.Herbs and spicesHerbs and ground spices keep good flavor up to one year if stored in cool, dry cupboards. Whole spices can keep their quality up to two years. Store them in a tightly covered container in a dark place. Air, light, moisture and heat speed flavor and color loss. If you use a spice rack, place it away from light, heat and moisture. Avoid storing above or near the stove, dishwasher, microwave, refrigerator, sink or heating vent. Use a dry spoon to handle spices or herbs. Don’t sprinkle them directly from the container into a steaming pot.To check the potency of a ground spice, smell it. If its aroma is immediate, strong and spicy, it should still add flavor to your foods.To test herbs, crush a small amount in your hand and smell it. If the aroma is still fresh and pleasant, it can still flavor foods. If there’s no smell or an off smell, toss it. Get into the habit of smelling your spices and herbs periodically; you will learn what fresh smells and looks like.Following these tips and paying attention to your stored staples can help avoid disappointments in your baking. Be sure to always read labels, follow storage information and look at recommended use-by dates for all ingredients.
Research entomologists in the University of Georgia College of Agricultural and Environmental Sciences (CAES) are using three grants to study ambrosia beetles in an effort to prevent future attacks and preserve more fruit and nut trees.The first grant, $10,000 funded through Southern Integrated Pest Management Center, supported the work of a team of entomologists, plant pathologists and UGA Cooperative Extension specialists at CAES who are working with growers to help identify different ways to combat the issues presented by ambrosia beetles.Shimat Joseph, an entomologist on the UGA Griffin campus, says the goal was to allow researchers to identify their specific research and Extension priorities. The grant allowed the group to understand and collate both basic biology/ecology and practical management information on ambrosia beetles, and assess the knowledge gaps guided by the feedback from growers and stakeholders.“The funding help us come together as group so that we can prioritize needs and pursue a larger grant to conduct the needed research in a collaborative manner,” said Joseph.The second grant, valued at $10,000 from Georgia Farm Bureau, will fund the survey and monitoring of wood-boring ambrosia beetles in tree nurseries, tree fruit and pecan orchards. The goal of the research is to determine which species of ambrosia beetles are attacking different types of trees in Georgia.Brett Blaauw, UGA Extension specialist in fruit entomology, will study the beetles throughout the season in fruit orchards to determine which species are common in Georgia and to determine whether they pose a threat to trees.While the researchers began working on this project this year, most of the research will be conducted next year.The third grant, $73,000 from the Georgia Department of Agriculture, will fund projects aimed at improving monitoring tools and finding management strategies for ambrosia beetles in tree nurseries and tree fruit and pecan orchards. This grant will allow UGA research entomologists to trap ambrosia beetles in nursery and orchard systems.“Part of our project is contingent on the growers and the attacks that they will be reporting to us,” said Angelita Acebes-Doria, an entomologist on the UGA Tifton campus. “Whenever we receive reports of growers having problems with ambrosia beetles we want to know to what extent the trees are being attacked and to verify the ambrosia beetle species responsible for the attacks.”If the ambrosia beetles are found to have damaged infested trees too severely, with the grower’s permission, the researchers will dissect the trees to determine the species attacking the trees and compare them to the species captured in the traps. The grant will fund materials required in the season-long trapping, including ethanol lures and bottle traps, as well as funding student research assistants.“Without these grants we would not have been able to complete the research,” said Blaauw. “I am grateful that agencies like the Georgia Farm Bureau and Georgia Department of Agriculture have grants that help support research projects like ours.”Ambrosia beetles are insects that burrow holes in the trunks of ornamental, fruit and nut trees that are under stress. Their attacks are normally associated with young trees that are not well established or trees subjected to flood conditions and frost damage.Multiple beetle attacks on a young tree can have detrimental effects on the overall health of the tree and, in extreme cases, can cause tree mortality.“The higher number of attacks on the trees, the higher the chance that the tree will die. They attack a wide variety of host plants, not just pecans,” Acebes-Doria said. “They can (also) attack nursery trees, ornamental trees, and they can attack tree fruits as well, such as peach and apple.”To learn more about the UGA Department of Entomology visit ent.uga.edu.
FacebookTwitterLinkedInEmailPrint分享The Portugal News:The production of electricity from renewable sources supplied 51 percent of national consumption in 2019, with wind power representing 27 percent, the highest share ever.Photovoltaic solar energy was, according to REN, the source that grew the most last year, having exceeded for the first time the value of a terawatt-hour (TWh) of annual production. The hydroelectric production index stood at 0.81 (below the average of 1) in 2019, with the last two months of the year improving dam production. In December, the production index reached 1.77. In turn, the wind production index registered 1.05 in 2019, and 1.13 in December.“The combination of these factors allowed a period of 131 consecutive hours, the longest ever, with renewable production exceeding consumption,” said REN.Thus, in December 2019, all renewable production supplied 76 percent of national consumption (including export balance) and non-renewable production the remaining 24 percent.The balance of trade with foreign countries relating to renewables was exporting (more was sold to Spain than was bought) and “was particularly high” in the last month of the year, equivalent to 19 percent of national consumption.More: Renewables supply 51% of electricity in 2019 Renewable energy provided 51% of Portugal’s electricity needs in 2019